This is the 165th fixture between these two sides in Italy's top division. The all-time form book puts Inter ahead on 70 victories to 47, with 47 draws as well.
The most frequent scoreline between these two teams in league encounters is 0-0, which has happened 20 times (most recently at the Stadio Olimpico in March 2014).
Roma have silenced the San Siro only 14 times in the history of Serie A, but have emerged victorious in four of their last ten league encounters against Inter here. The Nerazzurri have won 43 times in this fixture at home, while 25 draws account for the rest (82 games between the two in Milan).
Roma have finished the game with ten men in four of the last eight Serie A matches between these two sides played at the San Siro (two wins, one draw and one loss).
Roberto Mancini's team have picked up five 1-0 wins since the start of the season. No other team has registered more than three victories with this scoreline.
Until now, no team has ever won the Scudetto after only managing ten goals or less in the opening ten Serie A fixtures
Roma go into this match on the back of five back-to-back victories, their longest winning streak since April 2014 when it stretched to nine.
The Giallorossi have registered 25 goals in their first ten games this season. Roma have been more prolific in Serie A only once in their history, when they notched 26 goals over the same period of games in 1960/61.
Roma have struck 12 times in the opening 45 so far, more than Inter have managed overall.
Inter and Verona are the only teams not to have found the back of the net in the first half hour of play.
The Giallorossi have conceded five strikes in the final 15 minutes, no other team has let in more during this period.
Garcia's players are the deadliest in Serie A from dead-ball situations, having scored eight times.
Twelve different players have got themselves on the score sheet for Roma this season, more than any other club in Europe's top five leagues.
The Giallorossi are the only side this season not to have dropped points from winning situations, going home with three points in all seven matches where they've taken the lead first.