Yeah, there are some players that you know that just have "it". Cambiasso oozes of that.
- He had a significant locker room presence.
- He was tactically astute, possibly the most tactical player of the 2000s.
- He has experience being coached by the likes of Jose Mourinho, Vicente Del Bosque, Ramon Diaz, Cesar Luis Menotti and even Marcelo Bielsa on the national team briefly. Of course there was also Mancini, Ranieri, Pekerman, Rafa Benitez, Leonardo, Stramaccioni, Maradona, Basile, Marco Silva etc. He is smart enough to know what to filter from each and everyone and who he's more likely to emulate from the truly successful ones.
- He loves Inter.
- He was/is a hard worker.
- He is very well connected in the world of football, which matters a lot nowadays.
- He has a winning mentality and is one of the winningest players of all time and until recently iirc was the #1 in trophies in the world. Think Dani Alves surpassed him.
Andrea Pirlo on the other hand was a very talented player, with excellent vision and a great tactical understanding. But he was mostly talented. Whereas a similar player like Xavi was more of a tactical genius than a creative force, while they both share an amazing ability to see the game play out before anything. Which is also how Guardiola played. Neither relied entirely on talent to succeed, which players like Maradona, Ronaldo, Baggio, Recoba etc cannot say.
Cambiasso has all the tools and characteristics to become one of the greatest managers out there.
The only obstacle is the lack of experience as a manager and sometimes you cannot afford the risk if you're climbing up, this is usually reserved for teams that are already on the top, as you have to minimize the downside risk. But at the same time, you cannot really expect Cambiasso to gain valid experience by moving to a Serie B club or taking over Independiente or something. If you want him to gain experience relevant to Inter he either has to come to Inter (at any role, preferably assistant manager) or move to a mid tier league for a championship competing side. Not many will give him that chance and coaching his former club in Greece that makes Juventus look like boy scouts in term of corruption won't be much of a help in actual coaching experience.
Honestly, I'd give him the chance if it comes to that, but he'll need to be paired with people who have coaching experience in Serie A and championship experience in general. Someone like Walter Zenga as his assistant (who might be humiliated by the request, as he'd expect the opposite role) would actually be really beneficial. Zenga won the Serbian league for example with Red Star, something that people consider a good experience for Stankovic. Just saying...